Services – Animal Model
- Specializing in the preclinical assessment of fibrotic diseases
- Enhancing translatability through clinically relevant models and outcomes
- Led by physician-scientists
Alport Syndrome
Col4a3 knockout mouse
a model of human Alport syndrome and CKD in general with progressively declining GFR
Heart failure:
HFrEF & HFpEF
CKD associated heart failure, LAD ligation, TAC, PAB. Emphasis on cardiac function as well as structure
Primary (autoimmune) cholangitis
DDC-included cholangitis
Interstitial lung diseases
Bleomycin lung disease
Lung function by O2 saturation, lung mechanics
aeration by micro-CT scanning
Lung function by O2 saturation, lung mechanics
aeration by micro-CT scanning
Scleroderma
Bleomycin skin model
